Although the exact mechanism of action is not fully understood, clofazimine seems to interfere with cellular membrane functions, including ion transport and respiration, ultimately causing Mtb death (Cholo et al., 2017
Lastly, a wide range of soluble factors [e.g., BDNF and chemokine (C-X-C motif) ligand 1 (CXCL1)] released by astrocytes can have myriad effects on myelination, as found in rodents (Tsai et al., 2002
Such collaboration is leading to a new paradigm where natural multi-component interventions stand alongside single-target drugs in a complementary fashion
In this review, we describe how animal models and modern cell tracing and imaging methods have helped to identify the cell types involved in myelin regeneration
Every injection day, reference the screenshot instead of recalculating